Mouse LIM homeobox transcription factor 1-beta (Lmx1b) ELISA Kit

A sandwich ELISA from Assay Genie designed for quantitative measurement of mouse LIM homeobox transcription factor 1-beta (Lmx1b). It is intended for use with serum, plasma, tissue homogenates, cell culture supernates and other biological fluids, and the detection method is colorimetric with mouse reactivity.

The kit has a detection range of 0.625-40ng/ml and a sensitivity of 0.328ng/mL. Precision is reported with an intra-assay CV of 8.3% and an inter-assay CV of 10.4%, and specificity is stated for natural and recombinant mouse LMX1B. LMX1B is described as a transcription factor that plays a critical role in embryonic development, particularly in the differentiation and maintenance of dopaminergic neurons, with dysregulation implicated in neurological disorders including Parkinson's disease and other movement disorders.

The protein is localised to the nucleus with a reported molecular weight of 44,102 Da. UniProt annotation describes LMX1B as essential for the specification of dorsal limb fate at both the zeugopodal and autopodal levels. The kit is for research use only and is positioned within the neurosciences research area.