Mouse Leptin receptor (Lepr) ELISA Kit

From Assay Genie, this Sandwich ELISA is designed for the precise measurement of leptin receptor levels in mouse serum, plasma, and cell culture supernatants. The kit is reactive with mouse samples and accepts serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids. Detection is colorimetric, with a detection range of 0.312-20ng/mL and a sensitivity of 0.163ng/mL. The associated research area is cardiovascular.

Reported performance figures include an intra-assay CV of 7.4% and an inter-assay CV of 9.1%. The assay specifically recognises natural and recombinant mouse leptin receptor, also known by the synonyms B219, OB receptor, OB-R, CD295, LEP-R, Db, Obr (UniProt P48356). The leptin receptor is described as a key component in the regulation of energy balance and body weight in mice, with dysregulation of the pathway linked to obesity, diabetes, and other metabolic disorders, making it a relevant target for studies of metabolism, appetite control, and fat storage. Isoform E of the receptor is reported to antagonise Isoform A- and isoform B-mediated LEP binding and endocytosis. For research use only.