Mouse Keratin 18 (KRT18) ELISA Kit

Quantitative measurement of endogenous mouse Keratin 18 (KRT18), a type I cytokeratin and well-established biomarker of epithelial cell damage and hepatocellular injury, is supported by this Assay Genie ELISA kit. Caspase-mediated cleavage of KRT18 generates stable fragments that circulate during apoptosis, making the protein a useful readout in liver toxicity studies, epithelial cancer models, and investigations of epithelial barrier integrity in murine systems. The colorimetric plate-based format is supplied as a 96-assay kit containing pre-coated wells, calibrators, and detection reagents. Suitable sample matrices include serum or plasma, tissue homogenates, cell lysates, and cell culture supernatants, covering workflows from in vivo dosing studies to in vitro cell-based assays. Each vial of standard and conjugate should be handled according to the included manual; the unopened kit is kept refrigerated. The assay provides a robust tool for researchers profiling epithelial stress, hepatocyte death, or tumor progression in mouse models, with absorbance readout compatible with standard microplate readers.