Mouse Kelch-like protein 17 (Klhl17) ELISA Kit

From Assay Genie, this Sandwich ELISA kit is designed for the quantitative measurement of mouse Kelch-like protein 17 (KLHL17), also known as Actinfilin. The assay is specific for natural and recombinant mouse KLHL17 and uses a sandwich ELISA format with colorimetric readout (optical density measured at 450 nm).

Performance characteristics include a detection range of 62.5-4000pg/mL and a sensitivity of 31.42pg/mL. KLHL17 (UniProt Q6TDP3) is a substrate-recognition component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex; the BCR(KLHL17) mediates ubiquitination and subsequent degradation of GLUR6, and may play a role in actin-based neuronal function. The protein has a molecular weight of 69,732 Da.

The kit accepts serum, plasma, tissue homogenates, cell culture supernates and other biological fluids, supporting research into protein degradation, cell signaling and cytoskeleton organization. The manufacturer literature links KLHL17 dysregulation to cancer, neurological disorders and autoimmune conditions, making it a biomarker of interest across disease research. For research use only.