Mouse Kelch Like ECH Associated Protein 1 (KEAP1) ELISA Kit

KEAP1 (Kelch-like ECH-associated protein 1) functions as the principal cytosolic sensor that targets NRF2 transcription factor for ubiquitination under homeostatic conditions. This Assay Genie ELISA reagent enables quantitative measurement of KEAP1 levels in mouse specimens, supporting investigations into the NRF2-KEAP1-ARE antioxidant response element pathway.

Applications include studies of oxidative stress, inflammatory signaling, xenobiotic metabolism, and tumor microenvironment biology. Researchers employ this kit to assess KEAP1 expression in murine models of cancer, neurodegeneration, and chemical-induced hepatotoxicity, where dysregulation of NRF2 turnover contributes to disease phenotypes. Store kit components refrigerated upon arrival, protect from light, and avoid repeated freeze-thaw cycles of the standard. Each microplate-based workflow is intended for research use only in vitro.