Mouse Interferon-induced transmembrane protein 3 (Ifitm3) ELISA Kit

Assay Genie provides this Sandwich ELISA Kit for the quantitative measurement of Mouse Interferon-induced transmembrane protein 3 (Ifitm3). The assay is intended for research use only and is reactive with mouse samples, validated for use with serum, plasma, tissue homogenates, cell culture supernates and other biological fluids.

Performance characteristics include a detection range of 0.078-5ng/mL and a sensitivity of 0.037ng/mL. Specificity is directed against natural and recombinant mouse Interferon-induced transmembrane protein 3. Linearity was evaluated across serum, EDTA plasma and heparin plasma samples at dilutions of 1:2, 1:4, 1:8 and 1:16, with recovery, intra-assay CV and inter-assay CV values supplied with the kit.

IFITM3 is an IFN-induced antiviral protein that inhibits the entry of viruses into the host cell cytoplasm, permitting endocytosis while preventing subsequent viral fusion and release of viral contents into the cytosol. It is active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV) and human immunodeficiency virus type 1 (HIV-1). The protein also plays a critical role in the structural stability and function of vacuolar ATPase (v-ATPase). The kit is shipped at +4°C and stored at -20°C, with component-specific storage conditions detailed within.