Mouse Intercellular adhesion molecule 2 (Icam2) ELISA Kit

From Assay Genie, this sandwich ELISA kit is intended for the quantitative detection of mouse intercellular adhesion molecule 2 (ICAM2, also known as CD102). The assay is reactive with mouse samples and is validated for serum and plasma, with the manufacturer additionally listing tissue homogenates, cell culture supernatants and other biological fluids as suitable specimen types. The kit is specific for natural and recombinant mouse ICAM2 and is labelled for research use only.

Performance figures reported by the manufacturer include a detection range of 1.56–100 ng/mL and a sensitivity of 0.86 ng/mL, with an intra-assay CV of 6.8% and an inter-assay CV of 8.8%. Linearity has been examined in serum, EDTA plasma and heparin plasma across serial dilutions, and recovery has been assessed in serum and plasma. According to the accompanying protein information, ICAM2 is a ligand for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2) and may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion, mediating interactions important for antigen-specific immune responses, NK-cell mediated clearance and immune surveillance.