Mouse Inter-Alpha-Trysin Inhibitor Heavy Chain H4 (ITIH4?ELISA Kit

The ITIH4 protein (Inter-Alpha-Trypsin Inhibitor Heavy Chain H4) is a ~120 kDa acute-phase glycoprotein synthesized predominantly by hepatocytes and secreted into circulation, where it contributes to extracellular matrix stabilization and modulation of inflammatory responses. Quantitative measurement of mouse ITIH4 supports preclinical research on hepatic injury, sepsis progression, acute-phase reactivity, and remodeling of the tumor microenvironment in murine models.

Assay Genie's immunoassay is calibrated for the native mouse ITIH4 heavy chain and is applied to serum samples, plasma samples, tissue homogenates, cell lysates, and cell culture supernatants. Researchers in hepatology, inflammation biology, and biomarker discovery use the panel to profile acute-phase dynamics in wild-type and transgenic mouse strains, including models of liver fibrosis, endotoxemia, and cancer-associated inflammation.

The microplate kit contains a pre-coated plate, matched detection antibody, recombinant mouse ITIH4 standards, chromogenic substrate, and buffers sufficient for 96 individual determinations. Reagents should be refrigerated on arrival, allowed to equilibrate before use, and protected from light to preserve activity across the workflow.