Mouse Integrin alpha-V (Itgav) ELISA Kit

This Sandwich ELISA Kit from Assay Genie is specifically designed for the quantitative measurement of Integrin alpha V levels in mouse serum, plasma, and cell culture supernatants. The assay is reactive with mouse samples and is intended for research use only.

Key performance specifications include a detection range of 78-5000pg/ml and a sensitivity of 39pg/mL. Reported precision values are an intra-assay CV of 4.7% and an inter-assay CV of 7.1%. The kit shows specificity for natural and recombinant mouse Integrin alpha-V, and accepts serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. Synonyms associated with the target include Vitronectin receptor subunit alpha and CD51.

Integrin alpha V is a key protein involved in cell adhesion and migration processes, playing a central role in cell signaling and tissue development. Dysregulation of Integrin alpha V has been linked to pathological conditions including cancer, inflammation, and autoimmune diseases, making it a valuable biomarker for research. The target protein is a single-pass type I membrane protein located at the membrane, with presence at cell junctions and focal adhesions, and the associated research area is cancer.