Mouse Integrin alpha-L (Itgal) ELISA Kit

Assay Genie's Mouse Integrin alpha-L (Itgal) ELISA Kit is a sandwich-format immunoassay for the quantitative measurement of integrin alpha-L in mouse samples. The kit is reactive with mouse and validated for use with serum, plasma, tissue homogenates, cell culture supernates and other biological fluids, with specificity for natural and recombinant mouse integrin alpha-L.

Performance specifications include a detection range of 0.312-20ng/mL and a sensitivity of 0.18ng/mL. Integrin alpha-L, also known by synonyms including CD11a and LFA-1, is a cell-surface adhesion molecule implicated in leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody-dependent killing by granulocytes and monocytes. It functions as a receptor for ICAM1, ICAM2, ICAM3 and ICAM4, contributes to leukocyte adhesion and transmigration, and plays a role in lymphopoiesis. Dysregulation has been linked to autoimmune and inflammatory conditions, supporting its value as a research biomarker. The target protein is catalogued under UniProt accession P24063.

The kit is intended for research use only and is stored at -20°C, with shipping at +4°C.