Mouse Insulin-like growth factor-binding protein 4 (Igfbp4) ELISA Kit

Designed for quantitative detection in mouse samples, this Assay Genie ELISA kit targets insulin-like growth factor-binding protein 4 (Igfbp4) using a sandwich ELISA format. The kit is reactive with mouse Igfbp4 and is intended for the measurement of natural and recombinant mouse Insulin-like growth factor-binding protein 4 in serum, plasma, tissue homogenates, cell culture supernates and other biological fluids.

Performance characteristics include a detection range of 0.625-40ng/mL and a sensitivity of 0.312ng/mL. The protein targeted (UniProt P47879) is a secreted IGF-binding protein that binds IGF2 more than IGF1 and prolongs the half-life of the IGFs, modulating growth-promoting effects on cell culture and altering the interaction of IGFs with their cell surface receptors. Igfbp4 plays a role in cell growth, proliferation, and apoptosis, with dysregulation implicated in various diseases such as cancer, diabetes, and cardiovascular diseases, making it a valuable biomarker for related research.

The product is supplied as a colorimetric assay kit for research use only.