Mouse Importin subunit alpha-2 (Kpna2) ELISA Kit

Assay Genie provides a sandwich ELISA kit for the quantitative measurement of mouse importin subunit alpha-2 (KPNA2) in research samples. The kit is intended for use with mouse specimens and is compatible with serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids.

According to the manufacturer documentation, the assay has a detection range of 0.625-40ng/mL and a sensitivity of 0.325ng/mL, and shows specificity for natural and recombinant mouse importin subunit alpha-1 (UniProt P52293). The target protein is localized to the cytoplasm and nucleus, with a reported molecular weight of 57,928 Da.

Importin subunit alpha-2 functions as an adapter protein in nuclear protein import, binding substrates with simple or bipartite NLS motifs to facilitate transport via nuclear receptor KPNB1. Its dysregulation has been implicated in cancer and neurodegenerative disorders. The kit is supplied for research use only. Synonyms for the target include Importin alpha P1, Karyopherin subunit alpha-2, Pendulin, Pore targeting complex 58 kDa subunit, RAG cohort protein 1, SRP1-alpha, PTAC58, and Rch1.