Mouse IL-1R2 ELISA Kit (MOES01722)

Assay Genie's quantitative ELISA provides researchers with a tool to measure interleukin-1 receptor type 2 (IL-1R2) in murine samples. IL-1R2 functions as a decoy receptor that binds and sequesters IL-1 family cytokines, limiting pro-inflammatory signal transduction through the IL-1 signaling axis. This makes it valuable for in vitro studies of immune regulation, autoimmune disease models, and investigations of tissue repair and inflammation resolution.

The kit supports research use only applications including profiling receptor expression in cell culture supernatants, evaluating anti-inflammatory compound effects, and characterizing decoy receptor dynamics in experimental models where IL-1 dysregulation contributes to pathology. Each kit provides reagents for 96 individual determinations and supports cytokine pathway research across multiple experimental contexts, including investigations of sepsis, rheumatoid arthritis, and inflammatory bowel disease where altered IL-1R2 levels have been observed.