Mouse IL-18 BPc PharmaGenie ELISA Kit (SBRS1420)

Quantify interleukin-18 binding protein isoform c (IL-18 BPc) in murine samples with this ELISA kit from Assay Genie, part of the PharmaGenie product line. IL-18 BPc functions as a soluble decoy receptor that sequesters mature IL-18, dampening interferon-gamma-driven inflammatory cascades, and tracking its circulating levels is relevant to cytokine regulation studies, autoimmune disease models, and host-pathogen response work in mouse systems.

Configured for research use only and in vitro applications, the reagents support measurement of mouse IL-18 BPc across standard research sample types, including cell culture supernatants and blood-derived specimens from experimental animals. The workflow uses a microplate pre-coated with capture antibody, a biotinylated detection reagent, a streptavidin-enzyme conjugate, and a chromogenic substrate, with absorbance readout on a standard plate reader. All necessary buffers, diluents, and a recombinant IL-18 BPc standard are supplied.

Unopened kits should be stored refrigerated; reconstituted standards and prepared working solutions should be aliquoted and held frozen to preserve activity across repeated freeze-thaw cycles. Each lot undergoes quality control testing for reproducibility within the PharmaGenie line.