Mouse High mobility group protein HMGI-C (Hmga2) ELISA Kit

From Assay Genie, this Sandwich ELISA kit is intended for the quantitative detection of mouse High mobility group protein HMGI-C (Hmga2). The assay employs a colorimetric detection method and is validated for use with mouse samples, including serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. The kit is intended for research use only and supports applications in cancer research, as HMGI-C/HMGA2 functions as a transcriptional regulator, participates in cell cycle regulation through CCNA2, and plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes.

The assay provides a detection range of 0.156–10 ng/mL and a sensitivity of 0.09 ng/mL. Specificity is for natural and recombinant mouse High mobility group protein HMGI-C, also referred to as High mobility group AT-hook protein 2 (Hmgic) — a nuclear protein with a molecular weight of 11,819 Da that interacts with E4F1 (by similarity) and NEK2. The corresponding mouse Uniprot entry is P52927, with NCBI Gene ID 15364.