Mouse Hes1  (Transcription factor HES-1) ELISA Kit (MOFI01383)

Quantitative measurement of Transcription factor HES-1 in mouse samples is enabled by this colorimetric immunoassay from Assay Genie, supplied in a 96 Assays kit format. HES-1 (Hairy and Enhancer of Split 1) is a basic helix-loop-helix transcriptional repressor that operates downstream of Notch receptor signaling and is widely studied in neurogenesis, myogenesis, hematopoiesis, and stem cell maintenance. The kit supports medium-throughput studies tracking Notch pathway activity, developmental biology questions, and disease models where altered HES-1 signaling has been implicated, including certain leukemias and immune regulatory contexts. Reagents arrive ready to run, with components stored refrigerated prior to first use to preserve antibody binding activity. Because HES-1 expression can oscillate in many cell types and respond rapidly to signaling cues, careful and consistent sample collection is important for reproducible quantification. The assay serves investigators working with murine models of Notch-dependent processes who need a direct protein read-out of HES-1 abundance, complementing transcript-level analyses such as qPCR with a quantitative measurement at the protein level.