Mouse Hepatitis B virus X-interacting protein homolog (Hbxip) ELISA Kit

A sandwich ELISA from Assay Genie designed for the quantitative detection of mouse Hbxip (Hepatitis B virus X-interacting protein homolog), also referred to as LAMTOR5 / Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5. The assay uses a colorimetric ELISA detection method and is intended for research use only.

Quoted performance figures from the manufacturer include a detection range of 1.56-100ng/mL and a sensitivity of 0.68ng/mL. The kit is validated for use with mouse serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. Specificity is reported for natural and recombinant mouse Ragulator complex protein LAMTOR5 (UniProt Q9D1L9).

The target protein functions as part of the Ragulator complex in amino acid sensing and activation of mTORC1, a signaling complex that promotes cell growth in response to growth factors, energy levels and amino acids. The associated research area is cancer, with reported subcellular localisation in the cytoplasm and at the lysosome.