Mouse Heat shock protein beta-2 (Hspb2) ELISA Kit

From Assay Genie, this Sandwich ELISA kit is designed for the precise measurement of Heat shock protein beta-2 (HSPB2) levels in mouse serum, plasma, and cell culture supernatants. The colorimetric assay delivers high sensitivity and specificity, supporting accurate and consistent quantification across a range of research applications.

HSPB2 is a small heat shock protein implicated in the cellular stress response, where it helps protect cells from stress-induced damage and contributes to maintaining cellular homeostasis. Dysregulation of HSPB2 has been associated with neurodegenerative diseases, cardiovascular disorders, and muscle-related conditions, making it a useful biomarker for exploring disease mechanisms and potential therapeutic strategies. The kit is reactive with mouse samples, shows specificity for natural and recombinant mouse HSPB2, and is intended for research use only within the Neurosciences research area.

Reported performance characteristics include a detection range of 0.312–20 ng/mL, a sensitivity of 0.159 ng/mL, an intra-assay CV of 7.4%, and an inter-assay CV of 9.8%. Recovery ranges are 88–100% for serum and 90–102% for plasma. Compatible sample types include serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids. The target protein (UniProt Q99PR8) localises to the cytoplasm and nucleus, where it may regulate the kinase DMPK.