Mouse Growth Arrest And DNA Damage Inducible Protein Gamma (GADD45g) ELISA Kit

The GADD45g (Growth Arrest and DNA Damage Inducible Protein Gamma, also known as CR6) target measured here belongs to the GADD45 stress-sensor family, a group of low-molecular-weight (~18 kDa) acidic nuclear proteins induced by genotoxic stress and inflammatory cytokines.

Quantification with this Assay Genie ELISA kit supports research into p53-mediated DNA damage response, G2/M cell cycle checkpoint control, and innate immune signaling, where GADD45g is transiently upregulated by IL-2, IL-6, and interferon-gamma.

The assay is validated to selectively detect mouse GADD45g with no significant cross-reactivity observed for the paralogs GADD45a or GADD45b under standard conditions, enabling specific tracking of the gamma isoform in tissue homogenates and cell lysates.

Researchers studying hematopoietic stem cell maintenance, autoimmune inflammation, or stress-induced apoptosis pathways benefit from the quantitative readout when working with limited mouse samples. Store refrigerated at 4 degrees C and protect from light until first use.