Mouse Gremlin 1 (GREM1) ELISA Kit

Quantitative immunoassay from Assay Genie for measuring Gremlin 1 (GREM1), a secreted BMP antagonist, in mouse-derived samples. GREM1 binds BMP2, BMP4, and BMP7 and is implicated in kidney organogenesis, organ fibrosis, diabetic nephropathy, idiopathic pulmonary fibrosis, and tumor-stroma signaling, and researchers commonly profile it to track BMP pathway activity in murine disease models.

The kit is configured for 96 determinations and includes a pre-coated plate, lyophilized standards, detection antibody, and assay buffers needed to generate a calibration curve. The procedure is validated for mouse serum samples, plasma samples, cell culture supernatant, and tissue homogenate workups. Researchers use it for ELISA-based quantification of GREM1 protein expression in studies ranging from renal pathology to oncology research.

Components are supplied in single-use vials and the kit is intended for research use only, with reactivity confirmed against mouse targets. Recommended for downstream analysis of BMP signaling, fibrosis research, and investigation of GREM1 as a candidate biomarker in mouse models of human disease.