Mouse Granzyme M (GZMM) ELISA Kit

The Assay Genie Mouse Granzyme M (GZMM) ELISA Kit enables quantitative measurement of GZMM protein in murine samples, supporting immunological research into granule-mediated cytotoxicity. Granzyme M is a trypsin-like serine protease constitutively expressed in natural killer cells and induced in CD8+ cytotoxic T lymphocytes, where it contributes to target cell killing and modulates inflammatory cytokine release.

This makes the kit applicable to studies of tumor immunology, viral and bacterial infection models, transplant rejection, and innate immune cell function in mice. Researchers investigating NK cell biology, cytotoxic T cell activation, or immune evasion mechanisms can use the assay to compare GZMM expression across tissues, treatment groups, or genetic backgrounds.

The microplate-based format accepts tissue homogenates and cell lysates prepared from mouse organs or cultured immune cells. All reagents are supplied ready-to-use in a single kit sufficient for one full plate. Store the unopened kit refrigerated and protect from light; reconstituted standards should be aliquoted to limit freeze-thaw cycles. For research use only.