Mouse Granulins (Grn) ELISA Kit

Designed for the accurate quantification of granulins in mouse samples, this Sandwich ELISA Kit from Assay Genie is a highly sensitive and specific assay suited to a range of research applications. Granulins are proteins involved in physiological processes such as inflammation, wound healing, and immune response, and their dysregulation has been linked to various diseases, making them valuable biomarkers for studies into neurodegenerative disorders, autoimmune diseases, and cancer.

The assay is reactive with mouse samples and accepts serum, plasma, tissue homogenates, cell culture supernates and other biological fluids, with detection carried out by colorimetric ELISA. It is specific for natural and recombinant mouse Progranulin, recognising the protein also known by the synonyms Acrogranin, Epithelin/granulin precursor, Glycoprotein of 88 Kda, PC cell-derived growth factor, Proepithelin, GP88, PCDGF, PEPI, and PGRN (UniProt P28798). The kit is classified within the Epigenetics research area and is supplied for research use only.

Performance figures include a detection range of 0.078-5ng/mL and a sensitivity of 0.04ng/mL. In functional terms, Granulin-7 stabilises CTSD through interaction with CTSD, helping to maintain its aspartic-type peptidase activity.