Mouse Glycoprotein Ib Beta Polypeptide, Platelet (GP1Bb) ELISA Kit

Glycoprotein Ib beta polypeptide (GP1Bb) forms the beta subunit of the GPIb-IX-V receptor complex on the platelet surface, where it mediates initial adhesion to subendothelial von Willebrand factor during primary haemostasis. The Assay Genie Mouse GP1Bb ELISA Kit enables quantitative measurement of GP1Bb in mouse research samples, supporting investigation of platelet biology, thrombotic disease mechanisms, and inherited bleeding disorders such as Bernard-Soulier syndrome, in which loss-of-function variants in GP1Bb produce macrothrombocytopenia and defective platelet binding.

Plasma is the validated specimen type, with results generated from a standard curve calibrated against purified mouse GP1Bb standards. Each kit contains pre-coated microwells, detection antibody, standards, and assay reagents configured for 96 individual determinations, accommodating both small pilot studies and larger cohort screening of platelet-associated biomarkers in murine models.