Mouse Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit

GSK3β (Glycogen Synthase Kinase 3 Beta) is a constitutively active serine/threonine kinase that regulates glycogen biosynthesis, Wnt/β-catenin signaling, insulin signaling, and neuronal function. Aberrant GSK3β activity is linked to type 2 diabetes, Alzheimer's disease, bipolar disorder, and several cancers, making accurate protein quantification essential for pathway-focused research in metabolism, neuroscience, and oncology.

This colorimetric ELISA kit from Assay Genie is configured specifically for mouse reactivity and is validated for use with tissue homogenates and cell lysates. Each kit supplies reagents sufficient for 96 assays in a microplate-based workflow, enabling direct comparison of GSK3β protein abundance across experimental conditions, genetic backgrounds, and pharmacological treatments in mouse-derived samples. The assay is intended for research use only.

Typical applications include:

• Quantifying GSK3β levels in mouse tissues such as brain, liver, skeletal muscle, and pancreas
• Monitoring changes in GSK3β abundance following treatment with small-molecule inhibitors such as lithium or CHIR99021
• Supporting studies on insulin signaling, Wnt pathway activity, and tau phosphorylation
• Validating Gsk3b knockdown or overexpression in mouse cell lines and primary cultures
• Characterizing mouse disease models relevant to diabetes, neurodegeneration, and tumor biology