Mouse Glutamate Dehydrogenase 1 (GDH) ELISA Kit

Quantitative measurement of Glutamate Dehydrogenase 1 (GDH) protein in mouse samples is supported by this ELISA kit from Assay Genie. GDH is a mitochondrial matrix enzyme that catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia, connecting amino acid catabolism to the tricarboxylic acid cycle. It plays a pivotal role in hepatic urea cycling, pancreatic beta-cell insulin secretion coupling, and central nervous system neurotransmitter recycling. Researchers studying these pathways rely on quantifying GDH to assess mitochondrial function, metabolic flux, and tissue-specific regulatory responses.

Validated specifically for mouse reactivity, the kit provides 96 assays per plate and is intended for research use only. Common applications include metabolic disease research such as non-alcoholic fatty liver disease models, hyperinsulinism-hyperammonemia investigations, and studies of neurodegeneration where altered glutamate metabolism contributes to neuronal dysfunction.