Mouse Glutamate Decarboxylase 1, Brain (GAD1) ELISA Kit

This neuroscience-focused immunoassay from Assay Genie enables quantitative measurement of mouse Glutamate Decarboxylase 1 (GAD1), the 67 kDa cytoplasmic isoform responsible for synthesizing the inhibitory neurotransmitter GABA from L-glutamate in GABAergic neurons. The kit is supplied as a complete reagent set configured for 96 assays and is validated for use with tissue homogenates prepared from mouse brain regions.

Researchers studying epilepsy, anxiety disorders, Parkinson's disease, diabetes-associated autoimmunity, and synaptic plasticity rely on GAD1 quantification to evaluate inhibitory circuit function and to monitor the balance between excitatory and inhibitory neurotransmission. Each kit is intended for research use only and includes pre-coated microplate wells, detection antibody, standards, and assay buffers for routine laboratory workflows.

Reconstituted reagents should be stored refrigerated and protected from light; refer to the enclosed protocol for stability and freeze-thaw guidance. The assay is reactivity-tested against mouse samples and runs in a standard ELISA workflow. Whether mapping developmental changes in cortical GABAergic interneurons or profiling GAD1 expression in transgenic disease models, this kit offers a reproducible tool for neuroscience and neuropharmacology research.