Mouse GLDH (Glutamate dehydrogenase) ELISA Kit (MOES01086)

Glutamate dehydrogenase (GLDH) is a mitochondrial matrix enzyme that catalyzes the reversible deamination of glutamate to α-ketoglutarate and ammonia. Because circulating GLDH rises sharply with hepatocellular necrosis, it is widely used in preclinical studies as a sensitive biomarker of liver injury in mouse models. This quantitative immunoassay kit from Assay Genie is calibrated against the mouse enzyme and is supplied as a ready-to-run microplate package, including pre-coated wells, a detection reagent, recombinant standards, wash buffer, and substrate solution. Researchers in hepatotoxicity, drug-induced liver injury, urea-cycle, and metabolic-disease workflows apply the assay to quantify GLDH in mouse-derived serum samples, plasma samples, and tissue homogenate specimens obtained from laboratory studies. Absorbance is read on a standard microplate reader, and results are interpolated from the included standard curve to give a concentration readout per sample.