Mouse GITR/TNFRSF18/AITR PharmaGenie ELISA Kit (SBRS1376)

Quantitative immunoassay for immunology and tumor biology research, this Assay Genie kit targets mouse GITR (glucocorticoid-induced TNFR-related protein, also known as TNFRSF18 or AITR) in cell culture supernatants, plasma, and serum. The workflow supports investigations into autoimmune disease mechanisms, transplant tolerance, and cancer immunotherapy target validation in preclinical murine models. GITR functions as a co-stimulatory receptor expressed on regulatory T lymphocytes, activated CD4+ and CD8+ T cells, and NK cells, where it modulates T cell proliferation, effector function, and immune checkpoint signaling. Researchers studying immune regulation and checkpoint modulation in murine systems can leverage the mouse-specific reactivity of the assay. The kit ships as a complete 96-assay microplate package including a pre-coated microplate, detection reagents, standards, and buffers required to run the protocol. Both in vivo and in vitro studies of immune regulation can use this quantitative readout.