Mouse GDNF (Glial Cell Line Derived Neurotrophic Factor) CLIA Kit (MOES00289)

From Assay Genie, this chemiluminescence-based immunoassay kit enables precise quantitative measurement of Mouse GDNF (Glial Cell Line-Derived Neurotrophic Factor) in serum, plasma and other biological fluids. It uses a Sandwich-CLIA format in which standards or samples are combined with a pre-coated specific antibody, followed by a biotinylated detection antibody and an Avidin-HRP conjugate. The relative light unit (RLU) value is read on a chemiluminescence immunoassay analyzer and is positively associated with Mouse GDNF concentration, allowing quantification by comparison to a standard curve.

GDNF is a pivotal factor in neuronal development and survival, with a particular role in promoting nerve growth and protecting dopaminergic neurons in the central nervous system. This makes it a key target for research into neurodegenerative conditions such as Parkinson's and Huntington's disease. The kit is intended for the in vitro quantitative determination of Mouse GDNF in serum, plasma and other biological fluids, and it recognizes Mouse GDNF in samples with no significant cross-reactivity or interference between Mouse GDNF and analogues.

Reported performance characteristics include an assay time of 3.5h and a sample volume of 100μL. Sensitivity is 9.38 pg/mL and the detection range is 15.63-1000 pg/mL, with both intra-CV and inter-CV reported as < 15%.