Mouse Gamma-aminobutyric acid receptor subunit alpha-3 (Gabra3) ELISA Kit

This colorimetric Sandwich ELISA Kit from Assay Genie is designed for the detection of mouse Gamma-aminobutyric acid receptor subunit alpha-3 (GABRA3) levels in serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids. The assay is intended for research use only.

GABRA3 is a subunit of the GABA(A) receptor, the principal inhibitory neurotransmitter receptor in the vertebrate brain, which mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. The receptor is generally pentameric, with chains from alpha, beta, gamma, delta, and rho types. The protein localises to the cell junction, synapse, and postsynaptic cell membrane as a multi-pass membrane protein. Synonyms include GABA(A) receptor subunit alpha-3 and Gabra-3.

Stated performance figures are a detection range of 0.156-10ng/mL and a sensitivity of 0.087ng/mL, with specificity for natural and recombinant mouse GABRA3. The kit is supplied in a solid-phase format, stored at -20°C and shipped at +4°C. Associated database entries include UniProt P26049, NCBI Gene ID 14396, and a molecular weight of 55,398 Da.