Mouse Fucosyltransferase 8 (FUT8) ELISA Kit

FUT8 (alpha-1,6-fucosyltransferase) is the sole mammalian enzyme that installs core fucose residues onto N-linked glycoproteins, a glycosylation mark that tunes IgG antibody-dependent cellular cytotoxicity, E-cadherin-mediated adhesion, and TGF-beta receptor signaling. Quantitative measurement of FUT8 protein abundance in mouse tissue and serum samples is therefore a routine need in glycobiology, monoclonal antibody engineering, and tumor immunology laboratories. The Assay Genie kit ships as a 96 assays format with pre-coated microplate wells, calibrated standards, and detection reagents sufficient to process full experimental cohorts with internal replicates. The workflow accommodates mouse-derived samples including serum and tissue homogenates, fitting comfortably alongside downstream western blot, immunohistochemistry, or cell-based functional assays. Researchers commonly use the kit to compare FUT8 levels across wild-type and knockout strains, between tumor-bearing and control animals, or following siRNA, CRISPR, or small-molecule perturbations of the fucosylation pathway. Reagents arrive in single use aliquots and should be stored refrigerated between sessions; repeated freeze-thaw cycles of prepared working solutions should be avoided to preserve signal. Intended for research use only, the assay provides a quantitative protein readout that complements transcript-level and enzyme activity measurements in studies of glycan-dependent disease mechanisms.