Mouse Frizzled-8 (Fzd8) ELISA Kit

A sandwich ELISA kit from Assay Genie is designed for the quantitative detection of mouse Frizzled-8 (Fzd8) using a colorimetric detection method. The assay is reactive with mouse samples including serum, plasma, tissue homogenates, cell culture supernates and other biological fluids, and shows specificity for natural and recombinant mouse Frizzled-8.

Frizzled-8 is a receptor for Wnt proteins and a component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling, playing a role in regulating cell proliferation, differentiation and migration. Dysregulation of the Wnt pathway and FZD8 has been implicated in cancer, developmental disorders and neurological conditions, making this kit a valuable tool for studying these diseases and exploring therapeutic interventions. Reagents are stored at -20°C and 4°C, and the product is for research use only.

Performance characteristics include a detection range of 15.6-1000pg/mL and a sensitivity of 7.91pg/mL. Associated identifiers include the Uniprot entry Q61091 and a molecular weight of 73,045 Da. The gene is symbolised Fzd8, with the synonym Fz-8.