Mouse FGL2 (Fibrinogen Like Protein 2) ELISA Kit (MOES01020)

Fibrinogen-like protein 2 (FGL2) operates as both an immune regulatory cytokine and a prothrombinase, with the soluble form (sFGL2) secreted primarily by activated regulatory T cells to suppress effector T cell proliferation. Tracking circulating sFGL2 concentrations gives researchers a quantitative readout of immune tolerance and inflammatory status in mouse models. This immunoassay kit from Assay Genie targets mouse FGL2 and is supplied as a 96 assays format. Published applications include studies of fulminant viral hepatitis, where elevated FGL2 drives fibrin deposition and hepatocyte necrosis, along with transplantation immunology research on graft-versus-host disease and allograft tolerance. Investigative teams working on sepsis, experimental autoimmune encephalomyelitis, and tumor immune evasion also use FGL2 quantification to characterize regulatory T cell suppressive activity. Reagents should be stored refrigerated and protected from light to preserve enzyme activity. The kit supports in vitro research workflows in immunology, hepatology, and transplant laboratories.