Mouse FBXO2 (F-Box Protein 2) ELISA Kit (MOES01012)

The SCF ubiquitin ligase component FBXO2 (also called FBG1 or FBX2) is a glycoprotein-targeting F-box protein studied primarily in neuroscience, where it regulates neuronal protein quality control and ER-associated degradation of misfolded glycoproteins. Mouse models are central to FBXO2 research because the protein has been linked to neurodegenerative pathways, including BACE1 turnover relevant to Alzheimer's studies.

The Assay Genie ELISA kit quantifies mouse FBXO2 in mouse-derived liquid samples such as serum-type and plasma-type specimens, using a colorimetric microplate readout supplied as a 96-assay pack. Each kit includes a pre-coated microplate, recombinant FBXO2 standards, biotinylated detection antibody, assay diluent, wash buffer, streptavidin-HRP conjugate, TMB substrate, stop solution, and a printed protocol.

For research use only. Allow all reagents to reach room temperature before beginning the assay, and avoid repeated freeze-thaw cycles of the standard by preparing small aliquots on first use. Researchers investigating E3 ligase biology, SCF complex substrate turnover, glycoprotein clearance, or murine models of neurodegeneration can use this kit to measure endogenous FBXO2 levels across treatment groups, genotypes, or time-course experiments.