Mouse Factor Related Apoptosis (FAS) ELISA Kit

Quantitative measurement of mouse FAS protein is enabled by the Assay Genie Mouse Factor Related Apoptosis (FAS) ELISA Kit, a research use only tool for apoptosis pathway studies. FAS, also known as CD95, APO-1, or TNFRSF6, is a transmembrane death receptor in the TNF receptor superfamily that initiates extrinsic apoptosis after engagement by FasL on cytotoxic lymphocytes.

This complete reagent set includes a pre-coated microplate, lyophilized standards, biotinylated detection antibody, and streptavidin-HRP conjugate, supporting laboratory work in immune regulation, autoimmune disease models, and programmed cell death. Researchers investigating tumor necrosis factor pathways, T-cell homeostasis, or hepatocyte injury rely on FAS quantification to characterize death receptor expression in murine systems.

The assay supports in vitro workflows involving cell culture supernatants, tissue homogenates, and body fluid samples. Each kit contains reagents sufficient for one plate run, with a read-out compatible with standard laboratory equipment. Apoptosis studies often pair ELISA data with flow cytometry or western blot analysis to confirm receptor changes at the cell surface or in lysates.

Investigators studying caspase cascade activation, DISC complex assembly, or autoimmune lymphoproliferative syndrome (ALPS) in rodent models will find this tool directly relevant. The kit arrives ready-to-use with a detailed protocol and works for endpoint measurement strategies in immunology and cell biology laboratories.