Mouse ER alpha (Estrogen Receptor Alpha) CLIA Kit (MOES00250)

Designed for the precise quantification of Estrogen Receptor Alpha in mouse samples, this chemiluminescence immunoassay from Assay Genie uses a sandwich-CLIA format and is compatible with serum, plasma, cell culture supernatants and other biological fluids. The assay requires 100 μL of sample and is completed in 3 h 30 min.

Reported performance characteristics include a sensitivity of 37.5 pg/mL, a detection range of 62.5-4000 pg/mL, and a recovery of 80%-120%. The kit specifically recognizes Mouse ERα, with no significant cross-reactivity or interference between Mouse ERα and analogues observed.

Estrogen Receptor Alpha is a nuclear receptor that mediates estrogen signaling, regulates gene expression, and influences cell growth and differentiation, playing critical roles in development, reproduction and metabolism. Dysregulation of ER Alpha has been implicated in breast cancer, osteoporosis and cardiovascular disorders, and the kit is therefore relevant to research in cancer, epigenetics and nuclear signaling, neuroscience, and signal transduction.