Mouse Ephrin type-A receptor 3 (Epha3) ELISA Kit

From Assay Genie, this sandwich ELISA kit is designed for the quantitative measurement of mouse Ephrin type-A receptor 3 (EPHA3) in serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids. The kit is reactive with mouse samples and is intended for research use only.

EPHA3 is a receptor tyrosine kinase involved in cell signaling pathways, particularly in neuronal development and axon guidance. Dysregulation of EPHA3 has been linked to cancer and neurological disorders, making it a useful biomarker for investigating disease mechanisms and therapeutic interventions. The receptor binds promiscuously to membrane-bound ephrin-A family ligands, with preference for EFNA5, and participates in bidirectional signaling that regulates cell-cell adhesion, cytoskeletal organization, and cell migration.

Performance characteristics stated for the kit include a detection range of 0.312-20 ng/mL and a sensitivity of 0.16 ng/mL. It shows specificity for natural and recombinant mouse Ephrin type-A receptor 3 and is referenced under UniProt accession P29319.