Mouse Eosinophil cationic protein 1 (RNASE3) ELISA Kit

This Sandwich ELISA Kit from Assay Genie is designed for the detection of mouse Eosinophil cationic protein 1 (RNASE3) in research samples, using a colourimetric detection method. The kit is reactive with mouse and is suitable for serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. Listed synonyms for the target protein include Eosinophil secondary granule ribonuclease 1, Ribonuclease 3-1, EAR-1, RNase 3-1 and ECP 1.

According to the manufacturer's specifications, the kit has a detection range of 78-5000pg/mL and a sensitivity of 39.6pg/mL. The antibody pair shows specificity for natural and recombinant mouse Eosinophil cationic protein 1, which localises to the matrix of the cytoplasmic granule within eosinophils' large specific granule. A third-party supplier lists the format as a solid-phase ELISA with storage at -20°C and shipping at +4°C.

RNASE3 is described as a cytotoxin and helminthotoxin with low-efficiency ribonuclease activity and a wide variety of biological activities. It is reported to play a role in inflammatory responses and immune regulation and is considered a valuable biomarker in conditions such as asthma, allergic diseases and parasitic infections. The associated UniProt entry is P97426. The product is supplied for research use only.