Mouse Endothelin 1 (EDN1) ELISA Kit

The 21-residue vasoactive peptide Endothelin-1, encoded by the EDN1 gene, drives vasoconstriction, endothelial dysfunction, and hypertensive signaling in mammalian cardiovascular systems. This colorimetric competitive ELISA from Assay Genie delivers quantitative readouts for murine Endothelin-1 across biospecimens harvested from plasma or serum compartments, tissue homogenates, cell lysates, and cell culture supernatants, supporting both in vivo disease-model phenotyping and in vitro mechanistic studies of vascular, renal, and pulmonary pathophysiology. Each microplate is supplied pre-configured for 96 assays, with standard curve reagents calibrated against recombinant mouse EDN1 peptide. Research applications span atherosclerosis progression, ischemia-reperfusion injury assessment, diabetic nephropathy models, and pulmonary hypertension investigations, where EDN1 concentration functions as a circulating biomarker tied to upstream gene expression. Reagents should be stored according to the enclosed product insert and protected from light to preserve antibody binding activity. For research use only.