Mouse Endoglin PharmaGenie ELISA Kit (SBRS1346)

Endoglin (CD105) is a homodimeric transmembrane glycoprotein that serves as an accessory receptor in the transforming growth factor-beta (TGF-β) signaling pathway. It is strongly expressed on proliferating vascular endothelium and on mesenchymal cells, and it is widely used as a marker of neoangiogenesis in tumor, cardiovascular, and developmental studies. This Assay Genie kit provides the reagents needed to quantify mouse endoglin in research samples, supporting work on vascular remodeling, tumor angiogenesis, and endothelial dysfunction in murine disease models.

The kit is configured as a 96-assay immunoassay and is intended for in vitro research use only. It is validated for use with mouse plasma, mouse serum, and conditioned medium from cultured murine cells. Researchers investigating pre-eclampsia, wound healing, cardiac fibrosis, or angiogenesis-related pathways in genetically modified mice will find this kit valuable for measuring soluble endoglin levels and tracking changes across experimental conditions.

Each kit includes a pre-coated microplate along with the detection antibody, standards, and buffers required to run the assay in the laboratory. For best results, samples should be handled according to standard laboratory practice, and the kit should be stored under conditions specified in the product insert to preserve reagent activity across the shelf life of the components.