Mouse Endocan PharmaGenie ELISA Kit (SBRS1344)

Endocan (ESM-1) is a 50 kDa dermatan sulfate proteoglycan secreted by activated vascular endothelium, and quantifying it in murine samples is the basis of vascular inflammation and sepsis research. The Mouse Endocan PharmaGenie ELISA Kit from Assay Genie delivers a 96-assay colorimetric immunoassay purpose-built for this work, accepting cell culture supernatant, plasma, or serum specimens from mice. Endocan expression is upregulated by pro-inflammatory cytokines such as TNF-alpha and IL-1, so the assay supports studies of endothelial activation, tumor angiogenesis, and acute-phase responses in mouse models of disease. Researchers also apply this kit to preclinical drug screening, where changes in circulating endocan serve as a pharmacodynamic readout of vascular protection or injury. Components ship refrigerated; store refrigerated upon arrival and protect from light to preserve reagent activity through the stated shelf life.