Mouse Ectonucleotide Pyrophosphatase/Phosphodiesterase 2 (ENPP2) ELISA Kit

Autotaxin, the lysophospholipase D encoded by ENPP2, catalyzes hydrolysis of lysophosphatidylcholine into lysophosphatidic acid, a bioactive lipid that drives cell migration, survival, and inflammatory signaling. Investigators studying tumor microenvironment remodeling, fibrotic disease progression, and vascular biology rely on quantitative measurement of circulating ENPP2 as a biomarker or pharmacodynamic readout.

Assay Genie's Mouse ENPP2 immunoassay supports workup in murine models by quantifying native autotaxin across specimen types collected during in vivo studies, including whole-blood-derived fractions, tissue lysates prepared at point of harvest, and other body fluids suited to preclinical protocols. Unopened kit components should be stored refrigerated upon arrival; working antibody and standard dilutions are typically prepared fresh before each run.

The kit supplies reagents sufficient for 96 assays and is processed on a standard microplate absorbance reader, giving laboratories a reproducible way to compare enzyme expression across treatment cohorts without developing custom reagents. A pre-coated strip plate, lyophilized recombinant standards, biotinylated detection antibody, streptavidin-HRP conjugate, substrate, and stop solutions are packaged to run the full plate, with a lot-specific Certificate of Analysis documenting current performance benchmarks for the supplied reagents.