Mouse Dystrophin Associated Glycoprotein 1 (DAG1) ELISA Kit

Quantifying dystrophin associated glycoprotein 1 (DAG1), the precursor that is post-translationally cleaved into alpha- and beta-dystroglycan subunits bridging laminin in the extracellular matrix to dystrophin in the cytoskeleton, this Assay Genie ELISA Kit supports mouse model research into muscular dystrophy, congenital disorders of glycosylation, and laminin-binding complex biology.

Validated for quantitative measurement of DAG1 in mouse tissue homogenates, the kit enables studies of skeletal muscle, brain, and peripheral nerve tissue where dystroglycan abundance shifts track disease progression. Apply the workflow to Duchenne muscular dystrophy mouse models, mdx strain comparisons, or glycosylation-defective cohorts, where shifts in DAG1 expression inform mechanistic and therapeutic investigations.

Shipped as a complete kit configured for 96 assays in a standard microplate workflow, the product includes pre-coated plates, detection antibody, standards, and substrate sufficient for batched analysis. Store unopened components at the temperature indicated on the package insert to maintain antibody binding activity throughout the stated shelf life of the kit.