Mouse Dynamin-2 (Dnm2) ELISA Kit

Manufactured by Assay Genie, this Sandwich ELISA Kit is designed for the quantitative measurement of Mouse Dynamin-2 (Dnm2), a microtubule-associated, force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. The kit uses a colorimetric detection method and is intended for research use only.

Dynamin-2 plays an important role in vesicular trafficking processes, in particular endocytosis, and is involved in cytokinesis, the regulation of neuron morphology, axon growth and formation of neuronal growth cones, and the maturation of apoptotic cell corpse-containing phagosomes. Dysregulation of DNM2 has been linked to various diseases, including neuromuscular disorders and cancer, making this kit relevant to cancer research and to broader studies of disease pathology.

The assay is compatible with serum, plasma, tissue homogenates, cell culture supernates and other biological fluids, and detects both natural and recombinant mouse Dynamin-2. It delivers a detection range of 15.6-1000pg/mL with a sensitivity of 7.92pg/mL. Intra-assay CV, inter-assay CV, linearity and recovery data are provided with the kit. The associated UniProt entry is P39054, and the protein has a reported molecular weight of 97,733 Da.