Mouse DNASE1 (Deoxyribonuclease I) ELISA Kit (MOES00956)

The Assay Genie Mouse DNASE1 (Deoxyribonuclease I) ELISA Kit enables quantitative measurement of DNASE1 in murine samples, supporting research into DNA fragmentation, apoptosis, and extracellular DNA clearance. DNASE1 is a Ca2+/Mg2+-dependent endonuclease secreted by the pancreas and other tissues that cleaves single- and double-stranded DNA into oligonucleotides, and its activity is a key readout in studies of neutrophil extracellular trap (NET) degradation, inflammation, and systemic lupus erythematosus (SLE) using mouse models such as MRL/lpr. Researchers investigating pulmonary disease, autoimmune pathology, or cancer biomarker discovery can use this microplate assay to monitor enzyme levels in longitudinal samples, with precision data supporting reliable comparison across experimental cohorts. The kit is supplied as a complete, ready-to-use pack including pre-coated wells, detection antibody, standards, and substrate, allowing researchers to generate a standard curve and extrapolate sample concentrations without specialized instrumentation beyond a standard plate reader.