Mouse DNA- (apurinic or apyrimidinic site)lyase (Apex1) ELISA Kit

This Sandwich ELISA Kit from Assay Genie is designed for the quantitative detection of mouse DNA-(apurinic or apyrimidinic site) lyase (Apex1) in research samples. The assay has a detection range of 0.156-10ng/mL and a sensitivity of 0.08ng/mL.

Compatible sample types include serum, plasma, tissue homogenates, cell culture supernates and other biological fluids, and the kit is specific for natural and recombinant mouse DNA-(apurinic or apyrimidinic site) lyase. Apex1 (also known as APEX nuclease, Apurinic-apyrimidinic endonuclease 1, REF-1, Redox factor-1, APEN, or AP endonuclease 1) is a multifunctional protein that plays a central role in the cellular response to oxidative stress.

It functions as an apurinic/apyrimidinic (AP) endodeoxyribonuclease in the DNA base excision repair (BER) pathway and also exerts reversible nuclear redox activity to regulate the DNA binding affinity and transcriptional activity of transcription factors. For research use only.