Mouse Disintegrin and metalloproteinase domain-containing protein 17 (Adam17) ELISA Kit

A Sandwich ELISA Kit from Assay Genie designed for quantitating mouse disintegrin and metalloproteinase domain-containing protein 17 (ADAM17) in serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. The assay is specific to natural and recombinant mouse ADAM17 and is intended for research use only.

ADAM17 is a critical enzyme with roles in cell signaling, inflammation and immune regulation, and is notable for cleaving the membrane-bound precursor of TNF-alpha to its mature soluble form. The analyte is also known by the synonyms TNF-alpha convertase, TNF-alpha-converting enzyme, CD156b, ADAM 17, and Tace, and the kit falls within the Neurosciences research area. The product datasheet reports a detection range of 0.078-5ng/mL and a sensitivity of 0.043ng/mL.