Mouse Defensin Alpha 5, Paneth Cell Specific (DEFa5) ELISA Kit

Quantify murine Defensin Alpha 5 with this ELISA Kit from Assay Genie, supporting researchers studying Paneth cell biology and intestinal mucosal immunity. DEFa5 is a secreted antimicrobial peptide produced by Paneth cells residing at the base of the crypts of Lieberkühn in the small intestine, where it shapes the gut microbiome and contributes to innate host defense against bacterial and fungal challenge.

This 96-assay kit provides colorimetric measurement for mouse-specific DEFa5 quantitation, supporting investigations into inflammatory bowel disease models, Crohn's disease pathogenesis, host-microbe interactions, and antimicrobial peptide expression profiling. Researchers employ it to track DEFa5 dynamics in mouse models of enteric infection, barrier dysfunction, and mucosal inflammation.

Reagents and a pre-coated microplate support in vitro assay workflows read on a standard plate reader. Standard curve-based quantitation enables comparison of DEFa5 concentrations across experimental groups, treatment conditions, and time points. For research use only, the kit supports laboratories working on gut immunology, microbiome research, and Paneth cell-related disorders.