Mouse Cytochrome P450 1A1 (Cyp1a1) ELISA Kit

From Assay Genie, this Sandwich ELISA kit is designed for the precise measurement of Cytochrome P450 1A1 (CYP1A1) in mouse serum, plasma, tissue homogenates, cell culture supernatants, and other biological fluids. Specificity is reported for natural and recombinant mouse Cytochrome P450 1A1.

Quoted performance values include a detection range of 0.312-20ng/mL and a sensitivity of 0.156ng/mL. Intra-assay CV is 7.0% and inter-assay CV is 9.4%. Recovery averages 81% (range 80-87%) in serum and 83% (range 80-89%) in plasma.

Cytochrome P450 1A1 is a heme-thiolate monooxygenase that contributes to the metabolism of xenobiotics and endogenous substrates such as fatty acids, steroid hormones, and vitamins, and has been linked to detoxification and the activation of procarcinogens. Dysregulation of CYP1A1 has been associated with cancer, cardiovascular disorders, and metabolic syndromes, making it relevant to cardiovascular research. The UniProt accession is P00184, with a reported molecular weight of 59,230 Da. For research use only.