Mouse Cystatin-C (Cst3) ELISA Kit

From Assay Genie, this Sandwich ELISA Kit is designed for the precise quantification of Cystatin C (Cst3) in mouse serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. The assay recognises natural and recombinant mouse Cystatin-C, also known by the synonym Cystatin-3, and is for research use only. Reactivity is mouse.

Reported performance characteristics include a detection range of 7.8-500ng/mL and a sensitivity of 4.01ng/mL. Precision is given as an Intra CV of 4.3% and an Inter CV of 7.8%. Recovery data show an average of 88% (range 82-94%) in serum and an average of 90% (range 84-96%) in plasma. Linearity was assessed across serial dilutions of 1:2, 1:4, 1:8 and 1:16 in serum, EDTA plasma and heparin plasma, with the percentage ranges demonstrated across these matrices.

The target protein is a secreted inhibitor of cysteine proteinases that functions as a local regulator of this enzyme activity (UniProt P21460). The kit is assigned to the Neurosciences research area, reflecting the protein's described links to neurodegenerative and cardiovascular processes, and is associated with conditions including kidney disorders, cardiovascular diseases and neurodegenerative conditions.